Genetic genie vs promethease reddit Hey that's me. However, when I look at my DNA on 23andme, it shows that I I'm new to genetics so I don't fully understand what data I'm looking at and how to interpret it. My parents have done 23andMe and Ancestry. com. But. The UI is slightly better. Best pipeline for BAM -> [promethease friendly format]? Right now I'm planning to do a GATK transformation a la java -Xmx10g -jar GenomeAnalysisTK. And the studies on rs1805086 are flawed because they don't factor in a person's height or alpha actinin profile (whether they are predominantly fast-twitch, slow-twitch, or in-between) because that will have a huge impact on your ability to build muscle as 18 votes, 11 comments. Although I haven’t seen FMF reports since they did an update. I am seeing Hopkins Genetics in January. Members Genetic Genie Methylation Panel advice . Contradictory results between Promethease and genetic However, in my Genetic Genie detox panel, it is green (-/-) My quick and dirty basic searching seems to show that AA is the bad one. Customers retain 100% ownership of their own raw DNA data. I already knew my mom and had the BRCA1 gene(s) from a test I'd taken previously to specifically identify its presence, but I was pleased to see that This is the right answer. AncestryDNA is the best genotyping raw data for uploading to health raw data interpretation/analysis services such as Genetic Genie, GenVue Discovery, Promethease, StrateGene and Xcode Life, and others. Promethease options for multiple family members (comparisons, etc. But don’t think they looked at dopamine transporter gene you mentioned. com is a marketplace of a wide variety of different applications that interpret genetic data. In her Promethease (that I looked after the dr pointed it out) it’s marked as red and says she has 2-4x chances of Myeloproliferative Neoplasms. 6x increased risk for breast cancer 3 - fetuses with this genotype may cause maternal pre-eclampsia 3 - View community ranking In the Top 10% of largest communities on Reddit. so now i have an. Hi, I've been doing similar genetic reviewing. Anxiety is not. I had 4 things turn up for Lynch Syndrome. And just like Genetic Genie bases their reports on the ClinVar database, Promethease uses SNPedia as the data source for the information they give users. BRIP1 mutations do not cause cancer risks that are as high as the BRCA genes-- mutations in this gene may increase the risk of breast cancer, but right now it's recommended that women with mutations in this gene be screened according to their family history- so a consult Enlis Genomics: A similar service to Genetic Genie, but outputs a PDF gene report instead of providing a software tool for searching the report. rs138207610(A;G) high risk for colorectal cancer, magnitude of 7 - thoughts? Promethease said that it could be a false positive since it’s so high. There are several ways to check your DNA for SNPs. 341T>C, p. This is one where clinical testing would give you a clear answer. I’m perturbed. I uploaded my 23andme data to Genvue and other platforms like Nebula. Each item carries a brief description, details about biology, and an assessment of the medical significance. So then I uploaded the same raw data on promethease and it did not say I had any brca genetic mutations at all. Livewello - 20 dollars for for various reports generated from ancestry raw data files. This is secondhand info/opinion - I have a family member who works for a genetic testing lab. reddit. I recommend NOW brand 200mg Capsuals (not tablets), so you can open then and reduce the dose to 100mg to start. Mine is 4 for 1) being female and 2) rs1333049(C;C) - 1. I'm officially diagnosed as Autistic and suspected to have ADHD Combined Type. [Sometimes it will wind up in a spam folder rather than your inbox. I do fairly well on methyl B supplements to improve fatigue Folks, I(34F) am shit scared. Internet Culture (Viral) Amazing; Animals & Pets; Cringe & Facepalm Genetic genie and choline calculator results. From Genetic report. Genetic Genie- FREE Nutrahacker DNAFit Livewello StrateGene My Heritage- FREE DNA Land- FREE You can I got my genetic test months ago, I ran it through Promethease and Rhonda Patrick's own tool, I've read a couple of the top methylation posts here, watched some 'what is methylation' and Rhonda Patrick videos and general googling, and I still have no freakin clue what to actually do. PSA: '23 and Me' still provides your raw genetic data which can then be easily run through third party tools like 'Genetic Genie', 'Promethease', 'Sterling's App', 'LiveWello' and others I have encountered confusing information online (even a little bit here, DOH) where folks seem to think 23nMe has been shut down from the DNA side and can only Promethease is slightly more reliable, but there’s a fee yet there is virtually no customer service to show for it. 9K subscribers in the promethease community. I understand 23andme only does genotyping so I may not get a full, accurate picture. Or check it out in the app stores A place for discussing Promethease, a report about your DNA based on the scientific literature cited in SNPedia. All I've figured out is it's basically the most important thing to my health (and that I respond well to I did a Genesight test like 7 years ago. I have this and then a ton of good SNPs to Gene A is known to be associated with being tall. Promethease and heart disease family history of heart disease (dad died from MI) I’m on statins. What exactly is absurd about that? Thank you so much! Really appreciate all of your feedback. Btw, just in case anyone else is here to learn and also has issues with vitamin A - the gene for conversion of beta carotene to vitamin A (retinol) is BCMO1, and rs' are rs7501331 and rs12934922, with T being the variant. A place for discussing Promethease, a report about your DNA based on the scientific literature cited in SNPedia. Q&A. . Members Online • DeathByRamen91. ADMIN MOD Genetic Genie results - please help! According to the emails sent to Promethease users, MyHeritage is supposed to have created accounts and provided ancestry results for us as of today Get the Reddit app Scan this QR code to download the app now. g. Promethease has reported a rs121912441 with repute "good" but the text says "rs121912441, also known as c. There are third party sites like promethease, codegen, self decode, genetic genie, and nutrahacker that will scan your raw data and give you a list of your SNPs. codegen. If I am positive for the BRCA1 or BRCA2 genes, how will it be shown on Promethease. Promethease vs Codegen. MAO-A - Rauwolfia Serpentina Extra (Search Amazon), this will boost your MAO-A activity thus breaking down the massively excess serotonin you have and thus stabilizing your mood and reducing anxiety. It reminds me more of Genvue. Both of these came up on my report and I am not really understanding. You can upload your results, and they can give you a paid report summary and within that summary are links to articles explaining how the genetic alterations impact your What is the best way to apply the Genetic Genie detox profile? After some quick research, it seems I need more glutathione. But the promethease program don't show genes it shows all the snps inside a gene. I have results post-FDA-ban, and I'm not sure how the old data compares to Promethease. False positives . Or check it out in the app stores     TOPICS. I wonder why it wasn't marked in red as I vaguely remember prometheus marking in red color the bad stuff though might be wrong. And similarly you clearly don’t realise that most of the genetic data promethease is using is View community ranking In the Top 10% of largest communities on Reddit. This disease is listed in Promethease, but I'd never checked for it before. It is an annotation tool aimed at professionals. 60mg codeine does absolutely nothing for me and my results from my raw data from 23andMe and Ancestry (uploaded to a free online programme called Genetic Genie) suggested I was a CYP2D6 poor metaboliser with alleles *3 and *4 (both non-functional). There are also a lot of scammy websites out there wanting access to your private genetic data. I had my 23andme testing done in 2015, and got my Promethease, Genetic Genie and Stratagene reports, but didn't delve too deeply into them at that time. If you want a simple colored chart for the major ones use Genetic Genie. Currently, I am researching ways to address my condition from a genetic standpoint. In the genetic genie's genvue Trying to address Panic disorder, sensory overload, low stress tolerance, and fatigue. Genetic Genie (and other tools like this) simply pull data from public data repositories and then format the data for users to read. Also fine/normal activity on DRD2 (dopamine receptor). Controversial. I'm getting a (legit) genetic test done tomorrow - this test originally showed a brca2 and tp53 mutation which tracks with some family history. Also its an Isreali company with in itself is kinda sketchy. Posted by u/[Deleted Account] - 6 votes and 3 comments For example, I've discovered through Genetic Genie that I have two homozygous gene mutations that may or may directly influence depression. To access the full software costs $39. If you are male, you inherited this from your mother and your sons won't get it from you. I updated it today and it showed items which is feels are false positive (including a new brca 1) but then the The health report is presented as a list of relationships between users’ gene variants and health traits. com is more focused on family lineage, whereas 23andme places a greater emphasis on health and wellness. FMF gives more discussion, Promethease gives topical highlights and links to studies, etc. It does allow 23andMe input and you can run it against various databases that the program has modules for. Through additional research, I learned that unless Get the Reddit app Scan this QR code to download the app now. Hi! I downloaded my RAW DNA to genetic genie. Reply The 23andme reports are not diagnostic and are FDA approved for genetic risk. hg19. Or check it out in the app stores   gene mutation. People with your 13 votes, 51 comments. Help with Fastq files Get the Reddit app Scan this QR code to download the app now. Hello everyone, I see in my report that I have the highest magnitude for rs10151259, which is described on SNPedia as "Recessive genotype uncertain pathogenicity". rs28929474(A;G) and rs17580(A;A) Alpha-1 Antitrypsin Deficiency Carrier . Top. Why is that and which should I rely on going forward? You shouldn’t ‘rely’ on either. However, there are many other companies which can View community ranking In the Top 10% of largest communities on Reddit. If you live to 90 vs 80, your risk will be higher. RS45487699 (reported) Hi! I'm new here and into Promethease, but I was wondering if someone more experienced could help me "decode" this? I don't know whether this is telling me that I have an actually issue or not. How to access report you will receive an email from reports@promethease. Understanding GAA Gene Mutation. bam -- emitRefConfidence GVCF --maxAltAlleles 24 Your Promethease report said for each of those genotypes, "likely to be a miscall if from 23andMe data" or the equivalent. If you have any suspicion at all for having Marfan please do an echocardiogram to check your abdominal and thoracic aorta size it can save your life. MyHeritage test is 39€ here in Germany and AncestryDNA 69€, on the genetic genie website it states that AncestryDNA is the best data set of the consumer genomics company because they have the most clinically relevant data but is it really worth paying almost double The end result is the bell curve, and the scale is “where are you compared to all others, when considering all the known genetic markers of schizophrenia”. The fitness-related information you glean won't really be that big a deal and doesn't really mean much in the end, but you can find out if you're a poor methylator of various B vitamins, etc. User reviews Okay so I initially found out about my MTHFR from Rhonda Patricks Genetic report tool (which costs $25) and the results are screenshot below. I recently took a look at my father’s Promothease report and noted he has the Warrior Gene (G,G). It would also be important if One of the best resources I’ve found is genetic life hacks. Ok so I used WGSE (WGS Extract) to take my CRAM file and turn it into a file that would be accepted by promethease and genetic genie etc. Go figure. Both 23andme and Ancestry offer up a limited subset of genes for their customers. Alot of the "health" results are just over simplified explinations of studies done on SNP's you can also run through Promethease or Genetic Genie. ADMIN MOD Any Recommended Sites To Interpret Genetic Genie Results? Results Discussion Share Sort by: Best. Members Online my_shiny_new_account Two very useful sites that allow you to use your raw data are promethease and genetic genie. I just uploaded my AncestryDNA data to Promethease a few hours ago. Ile114Thr and I114T, represents a rare mutation in the SOD1 gene on chromosome 21. Unfortunately, the vast majority of currently actionable medical genetic results derive from individual case studies, extended family studies, and studies with under 1000, and usually 100, individuals, often within a disease cohort that raises significant barriers to broader population Would someone be able to help me understand how to read the reports for genetic genie? For example, a key for each row? I'm mostly interested in the difference between ref allele and alt allele (does this have to do with flipping?) and what the "variant" means (does this mean I have the alleles A;G? what does the c. Nebula offers lots of reports, IMO they are useless and poorly organized. To determine whether or not a particular gene is active or expressing in you, blood tests are recommended. Your mother has 1 SNP on gene B and was very short. I also have the same one but mine is marked with green (meaning good). Check out Genomapp. Looking at one SNP at the time is only appropriate for monogenic disease. I am a genetic counselor and have had to counsel on promethease results. The best thing is still to get an actual clinical test done. Blank Pages . psychiatrist, therapist, maybe even a genetic counselor), but the pace at which I have access to these clinicians, along with the limited duration of our sessions means exploring things Promethease If you choose not to create an account. The incident was blamed for leaking the data of more than 92 million users. GenVue Discovery is more focused on They will match any format against a bunch of different databases and produce a report that should be much more complete than promethease considering the price. bectherebel Using your 23andMe results, you can easily use the genetic analysis provided by Genetic Genie. There are reasons that some people with a gene end up with these disorders, and some don't, and we don't really understand them yet. My mum's side of the family all have the gene too. TiredBabyy As others have done, I plugged 23&me results into Genetic Genie, and got 4 different mutations for Lynch syndrome: MSH2 rs63750722 MSH6 rs63750940 MLH1 rs63751015 MLH1 rs63751200 Previous threads are at the bottom of the post I've collected from reddit of others who had this result. So finding out the degree your gene is impaired will be helpful. I'd like to talk to I’m quite fatalistic, so finding out which dodgy variants I’ve got doesn’t bother me. They compare your DNA data with that of millions of other people and find regions of similarity. A post today has the exact same results as you, they (genetic genie) reversed the reference call with the mutation call for all 4 of these. Gene variants are not a diagnosis. Add a Comment Some people can't tolerate methylated B vitamins due to genetic mutations like MTHFR or COMT issues. I just re-ran my same DNA file to get updated reports. Only thing which stood out was a 3. which can be a pretty big game changer if it's causing you to have a deficiency. It makes people more aggressive and antisocial. It seems this reddit is so controlled by pro-promethease people, that it's almost impossible to write anything negative about them without getting kicked to the end of the stack. If you decide to create the account they reserve the rights to share your data with their partners. Or check it out in the app stores   For more information than methylation and detox reports that you can get from Genetic Genie and Nutrahacker, look into Genetic LifeHacks. For discussion of genetics research, ethical and social issues arising from genetics and its applications, genetics career questions, etc. Impute. Posted by u/[Deleted Account] - 4 votes and 12 comments Yeah, most of what was on my Promethease report was little of this higher risk, a little of that lower risk for the same conditions, seemed like a wash. I’m fairly certain I have Gilbert’s, need confirmation of genetics . This last weekend I was using my wife's ancestry DNA and uploading it to some sites like genetic genie, and promethease to see what they said. 99 for one month. If anyone could give me any help, I'd appreciate it - or point me in the direction of where to start good research. I work in the medical field as a nurse and I felt like the results were somewhat complicated to understand even coming from a medical background. It will also download some multi-gigabyte databases on your computer. So far I’ve done 23andMe, Ancestry and Genos (full exome), which all went through Genetic Genie. View community ranking In the Top 10% of largest communities on Reddit. e. However, it is important to realize that neither provider offers full genome sequencing. It is documented, my family had extensive testing when I was a kid, and there is even a published paper that includes our case. Members Online • Rude_Economist9099. As inexpensive as $9. rs10151259(T;T) - Uncertain pathogenicity . )? I used to run the desktop version, but see that the Windows one is now kinda crippled. Do I have the alleles that put me at risk? Promethease vs genetic genie. In Promethease it is not very clear how a result of “two bad genes” vs “three good genes” (or any other combination) translates into a genetic risk I paid for the following medical grade PGx test last year; my GP signed the forms. Reddit iOS Reddit Android Reddit Premium About Reddit Advertise Blog Careers Press. Though nothing showed in my 23andme report, I have several variations, it seems, of BRCA1 and BRCA 2, as well as rs2981582(T;T). to be false positives - in data produced by 23andMe. Crohn's SNP and Fast Metabolizer . This subreddit is dedicated to those wanting to learn more and discuss the MTHFR (Methylene tetra hydro folate reductase) gene mutation. ] Contradictory results between Promethease and genetic genie. Familial hypercholesterolemia in child? Hi, so we had my 9 year old son's DNA tested through Ancestry. Unfortunately, GeneticGenie offers very limited advice on the matter, and I'm still left 7. Promethease will then say you have an SNP associated with being short and then elsewhere another with being tall. In short, I'm looking for software or a website that would help I got my 23andme results back and plugged my raw data into Genetic Genie, and after hours upon hours of delving into genetics research, I'm still a little lost. Gene B is known to be associated with being short. COMT - Low dose Same-E. Difference between (C;G) and (C;C) My mom potentially has Polycythemia Vera and the Dr pointed out to her SNP RS10974944. Best. 5K subscribers in the promethease community. As the name denotes, Ancestry. Am I correct in thinking this sounds rather serious? rs55705857 - 6x increased risk of brain and spinal cord tumors . 5 magnitude for a gene that indicated an 8. They were right on target with the disease which showed the highest risk. Due to financial reasons, I am currently off my methylphenidate medication, which I intend to return to in the future. It's kind of confusing, at least on mobile, but using rhe search bar and entering "COMT" returns nothing red or negative. That covers about 20 percent of pharma and OTC drugs, including psych and pain meds. jar -R /Reference/ucsc. BRCA gene in Promethease. For example thats how they transfer all of their data from Promethease to MyHeritage after the company acquisition. com (Whole Genome): rs1801131 TG They can also provide a 23andMe compatible dataset so you can use services like MTHFRSupport, Genetic Genie, etc. Recently, I You inherit your genetic code from your forebears. Therefore stuff like a BRCA mutation diagnostic test in which one View community ranking In the Top 10% of largest communities on Reddit. It’s easier to understand than Promethease. Promethease at least gives you a "magnitude" so you know how much faith to put into that report. Would anyone mind giving me a helping hand? I'm trying to figure out the problems in 1) my methylation cycle (in terms of substance buildup/absence), 2) the implications of those problems (in terms of View community ranking In the Top 10% of largest communities on Reddit. I’m a female. Another good one is Genetic LifeHacks which cost me about $30 for a year access. According to the company, passwords and email addresses were accessed by Do you know which genetic tests analyze this? I did Genomind genetics test and I definitely have issues with SLC6A4 (serotonin transporter) and am fine/normal activity on the 5HT2C (serotonin receptor). 313 mean? View community ranking In the Top 10% of largest communities on Reddit. A similar tool to Genetic Genie mentioned above, Promethease takes your DNA data upload and provides a comprehensive report on your genetic variants that you can navigate using their online tool. The more the similarity, the more closely you are related to that person. com test. My top 10 from Promethease was very helpful, wish I had Unfortunately I don't think anyone could reccomend using a 3rd party DTC company to do genetic testing, as they don't have the medical-grade quality controls in place and I am not sure they would test a particularly large number of loci related to mental health. I have found some free services and some paid reports that have been really helpful in addition to promethease. Back in 2020 I have taken a 23andMe genetic test and have today used its raw data to generate a Promethease report. com and got the results back yesterday. I don't think Dante provides much in the way of reports. Posted by u/HolidayPainter - 2 votes and 2 comments I uploaded both of my kids DNA to promethease under one report because I didn't realize it was supposed to be for just 1 person. 23andMe v5 Raw Data . I’m not really concerned but do you think this is something I should look further into? Contradictory results between I have pretty bad anxiety and depression, and was wondering if maybe there was a gene contributing to it (amino acid deficiency, b vitamins, mthfr You would need an ocular genetic counselor to really assess your risk but this is not an uncommon result at all and most people still don’t develop severe disease or disease at all. Instead t In a Promethease report, this is done automatically as Promethease correctly flips genotypes from each company's orientation into the orientation used by SNPedia. If you or your family has a history of BRCA-related cancer, you But it is even more technical than promethease is. Do not confuse this with the completely different warrior/worrier COMT gene. I am going in for reclassifiction, due to the genes 23 and me found (run them through genetic genie- they identify more of the EDS genes). That means that many of the changes in your genes that affect your response to a drug are shared But just because you don't have one of those genes doesn't mean you don't have adhd. These reports should not be taken seriously in isolation. NutraHacker and Genetic Genie were the most helpful to me regarding nootropics. In the genetic genie, it was the methylation and detox profile, and said that I have an issue with vdr taq as well as a CYP1B1 variant that affects estrogen production (had many hetero results as well). There is a bit of a learning curve but once toy spend hours reading through it and SNPedia, you will get far more out of it then anything else 23andme could offer. Hi there! I recently found out through my 23&Me account that I am an unaffected carrier of Pompe Disease, and through Promethease and Genetic Genie I learned that it was the Adult-Onset type. Which is correct? Also, on my genetic genie detox, I am red (GG, +/+) for CYP1B1 but it is not listed on Nutrahacker at all? Any idea why that GenVue Discovery by Genetic Genie is a free Promethease alternative, as well as an alternative to Codegen (codegen. A place for discussing Promethease, a report about your DNA based on the scientific literature cited View community ranking In the Top 10% of largest communities on Reddit. Genetic Life Hacks was the only one that flagged a fairly rare gene variant that was causing my chronic cough (Alha-1 Antitrypsin Deficiency). On a wild hair, after hearing that there may be a link between the MTFHR mutation and POTS symptoms and long haulers, I uploaded my Ancestry raw data from a few years ago to Genetic Genie. I also ran Promethease on Genos. I know that ADHD is more complicated than genetics and that if I really want to get the most reliable information I would need to work with my clinicians (e. Contradictory results between Promethease and I don’t have anything above a 3 besides my sex, but mine (all 3s) are: 3 - moderate (2. I use Promethease and I looked up UGT1A1 and found my rs887829 is (A;A). I recently ran my 23andme code through both Promethease and genetic genie, and they gave me dissimilar results. I also have several markers specifically associated with schizophrenia, autoimmune and neurological conditions but I won't include them here. It is true that many ongoing and upcoming genetics studies are incorporating very large sample sizes. Out of curiosity I ran them through Promethease and was surprised that the first result was Familial Hypercholesterolemia with a No to Promethease. Once I get the results and use Genetic Genie, how do I interpret Because even if you have good genetics you still need to train to have the best results. Schizophrenia - comparison. You happen to inherit both copies. The Promethease report contains genetic information from SNPedia. fasta -T HaplotypeCaller -I ~MyPersonalGenome. Terms & Policies Family history: my father died of ALS many years ago. com/r/promethease/comments/5vhh14/orientation_gut_check/ I noticed that In 2015 I used Promethease. me, Varsome and Enlis Genomics software. double mastectomy for women). However, we would argue that the GenVue Discovery platform and user experience is unrivaled and completely different than any other tools. There you will find the information you seek, though I can't help you as far as interpretation goes. Go to promethease r/promethease • by crystal4545. I ran it in Promethease and I dont see anything about slow COMT at all. me: A tool like Genetic Genie, but offers limited modules like rare diseases and drug response. Interpreting the Promethease results was quite straightforward but I have been having problems with making sense of my Genetic Genie results. Those people do better with hydroxocobalamin and folinic acid. 9x increased risk for coronary artery disease. Any advice would be greatly appreciated 4. I have an hEDS dx from decades ago (as do my children) and no genetics from the geneticist. 23 and me is not diagnostic. A list of anything you have tried and which was helpful or not would also help us help you. 76x) increase for risk in obese 3- 1. US $40 the tool These are all genetic predispositions and not facts. I paid $5 for a report online, but don't see where I can run sibling comparisons, etc. Or check it out in the app stores I submitted my raw data to both Promethease, Live Wello, and Genetic Genieand I have no idea how to read these reports! One of the pages in the promethease report you can download shows a looong list of conditions, and there are red and View community ranking In the Top 10% of largest communities on Reddit. You can learn about which foods to eat, mood issues, health conditions, nutrient interactions, and much more. I love Promethease. I also have had intermittent elevated bilirubin levels throughout my life. Patient came to because according to promethease they have a pathogenic BRCA2 mutation (high risk for various types of cancers) if this finding is legitimate you would be recommended to have major preventative surgeries (I. Also Promethease which is a small fee. which used to be an option I thought I would ask here since a lot here use genetic genie. A place for discussing Promethease, a report about your DNA based on the scientific literature cited Get the Reddit app Scan this QR code to download the app now. I have my DNA through Ancestry-dot-com, and there are places you can upload it to see about how your genes may affect your health like a methylation panel and detoxification panel—Genetic Genie and Nutrahacker which are free. Promethease will cross reference your DNA with an SNP database which will highlight which genes you have which have SNP polymorphisms and show you detailed information that 23adnme is restricted from discussing on their site due to FDA regulations. Of those, 2 have raw data that specifies they were processed on a v4 chip, and 6 were processed on a v5 chip. Genetic Genie + NutraHacker Contradiction on Bhmt-08 Gene Genetic Genie says Bhmt-08 CC is normal/green/(-/-) but NutraHacker says CC is homozygous/red/(+/+) comments sorted by Best Top New Controversial Q&A Add a Comment. There are many more genes/snp that cause EDS. Its got a few more mutations listed versus Genetic Genie and has a small bit of an interpretation with each of the client’s most pertinent SNPs. Genetic ancestry tests use these markers to track your lineage and report ancestry and ethnicity. I didn't find it particularly useful or special. Dante Labs's BAM file link and Promethease. And there are a lot more. I did 23andme earlier this year and finally got the raw data. Promethease does not sell genetic data to third parties. Does Promethease/23andme detect large deletions in BRCA1? When I search the BRCA1 gene in my Promethease, I come up with 311 results - 306 good, 3 not set, and 2 bad (magnitude 2). What do I need to do to get the information? Contradictory results between Promethease and genetic genie. Because of recent elevated homocysteine levels and B12 deficiency in the past I'd like to make a MTHFR analysis. I requested an update promethease report and was sent a report with blank pages. Both of these companies have issues with false positives or for flagging benign mutations as pathogenic, but their opinion is that Promethease is worse for it. Before starting you should know that the gene variants are genetic predispositions only. Sorry I am very confused about this. rs12248560: https: //www Gene Freq Max Magnitude Publications 0 rs2241880(C;C) Contradictory results between Promethease and genetic genie. it's worth the price to upgrade. Was pleased that I didn't have the nasty ApoE 4 gene variant. I took the 23andme genetic test and put my raw data through promethease and it returned 4 different markers for ADHD, which is I used Promethease a while ago to look up some select gene results for things like drug metabolism, but I avoided looking at the health notes because there would be too much distressing data points with too little useful impact. The new report (since they were bought by the Israeli company) There is a ton of information hidden in your genetic raw data file. If you tend to be a nervous or anxious person I would avoid methyls and methyl donors. It said MTHFR issues and reduced activity COMT. Promethease will report on hundreds or thousands of snp’s, FMF only reports on a limited number of snp’s for which it has a decent body of info on. eu for free. Since my health has continued to deteriorate in recent years, and with no other answers, I Genetic genie is full of errors, switching calls for mutations with the "normal" sequence. Contradictory results between Promethease and 7. I suppose its benefit was that it wasn't as restricted as Genetic Genie or Nutrahacker in what you could search for. Hi! The promethease program don't show genes it shows all the snps inside a gene. EDS . So I am worried that I may I have a particular congenital eye disease caused by a genetic mutation. I received my report in May 2023 and ran it through Promethease. 95. Not sure if I understand this correctly, but it seems that promethease and selfdecode are reporting different results for the same variant: Selfdecode: You carry one "farmer" and one "hunter-gatherer” variant. The minor rs121912441(C) allele is considered an autosomal dominant mutation leading to amyotrophic I couldn't find any information, but I am going to take my 23 and me test soon. I'm creating this post to know if anyone has actually been able to get the BAM file link throught INSPECT as the SNPedia post states (https Contradictory results between Promethease and genetic genie. I had 23andMe done in April 2023 (v5 Chip). If you ever done 23 and me or ancestry DNA you can run your raw data through a site like genetic genie and figure out if you have a methylation issue or not. Simply download your 23andMe raw data and upload it into the Genetic Genie Site to get started! Unfortunately, it does not seem that Genetic Genie takes samples from other testing services. There's still A LOT we don't understand about genetics and the way genetics interacts with environments. New. Promethease is much more difficult to understand but I strongly suggest it. This is a Wiki-style site (like Wikipedia) that contains a lot of information on genetic mutations and variants that can be used to understand family history, including information about the increased risk of certain medical conditions such as Alzheimer’s disease. While Promethease is a single application that provides an interpretation of genetic data, Sequencing. Enlis Genomics might be more friendly for you to use. eu - a free promethease-ish service for ancestry testing raw data. com when your report is ready. This could very easily be a free resource relative to what other services offer for free (think genetic genie, snpedia) or very little (promethease $12). Hey y'all, I'm 23 y/o M. At least based on my long-ago usage of it, I can't think of a I can guarantee you have absolutely no idea the level of scrutiny a medical level genetic test goes through before results are issued - they actually have committee meetings to discuss them. Get the Reddit app Scan this QR code to download the app now. Members Online Harvard Study reveals 72% of the US public approves selecting embryos based on DNA (polygenic scores) for likelihood of developing conditions and traits. Question Hi All, Looking for input on what to think of this panel and advice on diet/supplements that may be helpful. 23andMe has completely excluded health and drug info from the new format. I’ve had DNA testing through Ancestry and uploaded to Promethease. Hi I ran my 23andme raw data through genetic genie and the results came back and said I had a homozygous brca1 mutation. Promethease did experience a security breach in 2018. I have had B-12 level tested, it was normal, but Posted by u/[Deleted Account] - 4 votes and 1 comment That post is very valid in this question, just replace promethease with genetic genie - they use the same approach. (Deep) from Nebula and used commonly available and well-known analyzes like Genetic Genie, Promethease, and Gene. 95-$79. View community ranking In the Top 5% of largest communities on Reddit. The marketplace contains almost 100 DNA analysis applications and continues to increase in size with new DNA analysis applications being added each month. Genvue showed me some very concerning diseases (LBS Type 2 -aortic dissection risk), cancer & heart stuff, potential sex reversal, Chromosome Y mosaicism, Parkinson and Crohn's) The list was long, also around the rare diseases. I thought that the $30 was well worth it. WGSE noted 47 chromosomes and did show the Y chromosome and then when I loaded the data to promethease I got this genoset (gs261). I am guessing you are an intermediate metabolizer. About a year/year-and-a-half ago, I did 23andme and uploaded my information into promethease and genetic genie. Both Genie and Prom correctly picked up my carrier status for a common recessive condition, but both missed the second (rarer) disease for which I’m also a Perhaps MAOA 3 repeats: Warrior Gene?People with this SNP may also have the 3 repeat version of MAOA, known as the Warrior Gene. So you have it from one parent. With 637,469 The only way I can look at my genetic results that I did with ancestry is trough the website promethease. So I just got 8 of 12 reports back from 23andme this week, still waiting on a few more. iobio (where I spent the most time, but it's difficult to search individually). Is one more accurate than the other? Yes, I think Genetic Life Hacks is the most useful one I have used, including Promethease, Genetic Genie, and Nutrahacker. eu), Impute. Otherwise you cannot be sure that a particular supplement will even help you. Old. I have a diagnosis of hEDS - is this something to worry about? this is the exact variant that was flagged on my report from Promethease using DNA data from my ancestry. If you really want to get a genetic test done, get a general, affordable one, like 23andme. That means we (SNPedia/Promethease) are telling you that based on what we've learned by comparing the data from many companies, those positions happen to be ones prone to being 'miscalled' - i. Open comment sort options. I recently uploaded my 23andme raw data in Promethease and found that, even though I have VERY VERY vividly red hair, the only red hair variant I Get the Reddit app Scan this QR code to download the app now. Some traits are better understood than others. Puzzleheaded-Pay641 View community ranking In the Top 10% of largest communities on Reddit. Can someone help me understand the Promethease variants based on the RAW DNA files and the Promethease report? Here are my DNA results: Promethease : rs1801131(A;C) Ancestry: rs1801131 TG 23andme: rs1801131 GT Sequencing. Contradictory results between Promethease and genetic genie. Or try a service that "productizes" this such as Genetic Genie or Codegen. At the most basic level, you can start reading Clinvar and SNPedia for subjects that may interest you. Blood tests, when available, and symptoms determine if a predisposition has been triggered or It could be a false positive, but could also be true. I then more recently ran the exact same data (AncestryDNA) through Each gene variant reads differently, but the A;G on the top left indicates one is plus and the other minus. Changes to move away from Orientation are coming soon https://www. I was trying to upload a family member's myheritage raw data onto genetic genie, it works for the methylation profile but it wont work for the genvue variant analysis part. 2 times higher risk of macular degeneration. If instead you are asking for sample reports from Promethease, they provide theirs on their website. (The top one seems to have the answer, the others I've What you’re focusing on, though, are the SNPs that have an effect on gene or protein function and health outcomes. It can't be trusted in any way for medical testing. It’s also age related. naje jebnw ebc woqci irc macr climtwz jbkrc arjuiq hnqgsh